Prevalence of neurological symptoms in newborns with withdrawal syndrome A single-center observational study.

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Janeth Michell Neder Chusán
Santiago Javier Peña Sempértegui
Rovel Belizario Mena Bonilla

Abstract

Introduction: Neonatal abstinence syndrome is a growing global problem caused by the rapid increase in drug use. It is characterized by neurological symptoms such as high-pitched cry, tremors, seizures, lethargy, Moro reflex, and hypertonia up to two weeks of age. The objective of this study was to measure the prevalence of withdrawal syndrome in children of mothers who use drugs.


Methodology: The study was a prevalence, descriptive, and observational study. The primary source of information was a database provided by the Liborio Panchana Sotomayor General Hospital. This database included all patients who received a final diagnosis of "withdrawal syndrome" during the study period.


Results: Thirty-four newborns with withdrawal syndrome were recorded; 64.71% were male. The mean age at which clinical manifestations appeared was 1.35 days. High-pitched crying was the most frequent symptom in 29.41% of cases. The substance most commonly used by pregnant women was "H," accounting for 91.2% of all cases.


Conclusions: These results confirm the importance of establishing timely detection and management protocols to ensure appropriate treatment for at-risk newborns, thus addressing a growing public health problem.

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How to Cite
Prevalence of neurological symptoms in newborns with withdrawal syndrome: A single-center observational study. (2025). Actas Médicas (Ecuador), 35(2), 106-112. https://doi.org/10.61284/235
Section
Original Research
Author Biographies

Janeth Michell Neder Chusán, Medical School, Faculty of Medicine, Catholic University of Santiago de Guayaquil, Ecuador.

Medica por la Universidad Católica de Santiago de Guayaquil, (Guayaquil 2022).

 

Santiago Javier Peña Sempértegui, Medical School, Faculty of Medicine, Catholic University of Santiago de Guayaquil, Ecuador.

Médico por la Universidad Católica de Santiago de Guayaquil, (Guayaquil 2022). 

Rovel Belizario Mena Bonilla, Medical School, Faculty of Medicine, Catholic University of Santiago de Guayaquil, Ecuador.

Doctor of Medicine and Surgery from the University of Guayaquil (Guayaquil, 2004). Specialist in Gynecology and Obstetrics from the University of Guayaquil (Guayaquil, 2004).

How to Cite

Prevalence of neurological symptoms in newborns with withdrawal syndrome: A single-center observational study. (2025). Actas Médicas (Ecuador), 35(2), 106-112. https://doi.org/10.61284/235

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