BLOOD CULTURES IN THE ION SOLCA PEDIATRIC SERVICE GUAYAQUIL JUNE 2018-2019.

Abstract

INTRODUCTION: The increasing antibiotic resistance to isolated microorganisms in blood cultures in neutropenic patients makes continued monitoring of the germs and their antibiotic susceptibility essential.

MATERIALS AND METHODS: A prospective study was designed using blood cultures from March 2018 to June 2019 from patients with febrile neutropenia hospitalized in the pediatric area of ION SOLCA Guayaquil.

RESULTS: Out of the collected 634 blood cultures, a positivity of 15.7% of cases was found, with a clear trend toward Gram-positive bacteria, accounting for 8.5% of the total isolates. Staphylococcus aureus represented the most common species among the Gram-positive, isolated in 31% of cases, followed by Staphylococcus hominis (20%) and Staphylococcus epidermidis in 18% and Escherichia coli in 30% of the Gram-negative group. Regarding the sensitivity found, Gram-positive bacteria (coagulase positive) had 100% sensitivity for linezolid, vancomycin, and tigecycline. In comparison, Gram-negatives maintained a sensitivity of 92% to amikacin, 35% to cefepime, 35% to ceftazidime, 64% to ciprofloxacin, 100% to imipenem, 100% to meropenem, 71% to piperacillin-tazobactam, and 97% to tigecycline.

CONCLUSION: The incidence was more significant for Gram-positive bacteria. There is a good sensitivity to vancomycin, linezolid, and tigecycline for Gram-positive bacteria and to amikacin, carbapenems, and Gram-negatives. Multidrug-resistant KPC bacteria were only sensitive to tigecycline and colistin.