Prediction of preeclampsia with the determination of serum homocysteine A single-center observational study.

Abstract

Introduction: The present study aimed to evaluate homocysteine as a predictor of preeclampsia in pregnancies from 12 to 20 weeks.

Methods: This was observational, longitudinal, and prospective research. The study population was patients who attended their first prenatal care visit between 12 a.m. and 8 p.m. weeks, the random sample included 360 patients whose serum homocysteine was determined. 48 pregnant women who did not meet the exclusion and inclusion criteria were excluded.

Results: Homogeneity was found among the patients, 270 patients (86.5%) had a normal pregnancy, 27 women (8.65%) had gestational hypertension, 9 (2.88%) had mild pre-eclampsia and 6 patients (1.9%) had severe pre-eclampsia, no cases of HELLP syndrome were observed. An increase in homocysteine levels was observed in 9 women who were not related to hypertensive disorders of pregnancy.

Conclusions: In the present research it was not expressed that homocysteine is a predictor of hypertensive disease of pregnancy.