intracranial hemorrhage

Abstract

Hemophilia is a disease of genetic origin, recessive and linked to the X chromosome; where factors VIII or IX are altered, causing a functional and quantitative deficit called haemophilia A and B, respectively.

These pathologies considered as congenital coagulopathies have very similar clinical manifestations. In addition, only men can present it; and women are considered carriers of the disease. Depending on the factor levels, it is classified as severe (<1% of normal value), moderate (1-5% of normal value), or mild (5 to <40% of normal value). It is characterized by spontaneous or provoked bleeding, usually secondary to trauma in deep localization sites, such as joints, muscles, and less frequently, but more seriously, in the central nervous system with significant morbidity and mortality.

Below we present the case of an infant with an intraparenchymal hematoma of the central nervous system as clinical debut of hemophilia.

B (factor IX deficiency) where emphasis is placed on clinical manifestations, studies performed and therapeutic management; Likewise, a brief and clear bibliographic review is detailed that includes basic and practical concepts for the appropriate approach to hemophilia B, since it affects the quality of life of patients and those around them.