Prognosis and risk of death in patients with acute coronary syndrome without elevation of the S-T segment A single-center observational study, application of the GRACE scale

Abstract

Introduction: The GRACE score is a validated tool for predicting in-hospital and 6-month mortality in patients with acute coronary syndrome (ACS). The study aimed to measure the mortality of patients with ACS without ST-segment elevation.

Methods: The present observational study was conducted at the Teodoro Maldonado Hospital in Guayaquil, Ecuador, from January to June 2019. The variables were age, comorbidities, sex, systolic blood pressure, serum creatinine, biomarkers of myocardial damage, electrocardiographic changes in the ST segment, and Killip and Kimball classification. In-hospital mortality and mortality six months later were measured. The sample was non-probabilistic. Non-inferential and inferential statistics are used.

Results: 100 cases are analyzed. By the GRACE scale upon hospital admission, 47% (n=47) were at high risk, 33% (n=33) were at moderate risk, and 20% (n=20) were at low risk. Patients evaluated at 6 months, mortality increased in patients considered high risk to 70 cases; patients with intermediate risk maintained the same probability of mortality, which was represented by 22% (n=22), and observes that patients with low risk at 6 months were represented with 8% (n=8), indicating that all patients evolved to be HIGH RISK.

Conclusions: In this study group, there were no differences in mortality between hospital admission and 6 months later. All mortality cases were high-risk.